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Centre for Bone Marrow Transplant >> Treatment Offered >> Allogeneic Transplant

Allogeneic Transplant

Allogeneic bone marrow transplant (BMT) involves using the stem cells of a donor. The donor may be a relative, usually a brother or sister, or an unrelated (anonymous) donor. The donor needs to be Histocompatible Leukocyte antigen (HLA) match.

  • » Sibling Donor Transplant
  • » Match Unrelated Donor
  • » Haplo- identical Transplant
  • » Cord Blood Transplant

Indications of Allogeneic BMT
Nonmalignant diseases

Bone Marrow Failure States, including:

  • » Severe aplastic anemia
  • » Fanconi’s anemia
  • » Paroxysmal nocturnal hemoglobinuria (PNH)
  • » Pure red cell aplasia:Acquired and inherited (DBA)
  • » Amegakaryocytosis / congenital thrombocytopenia

Immunodeficiency states

  • » Severe combined immunodeficiency (SCID)
  • » Wiskott-Aldrich syndrome
  • » Chediak-Higashi syndrome
  • » Congenital neutropenia

Metabolic disorders

  • » Hurler's syndrome (MPS-IH)
  • » Adrenoleukodystrophy
  • » Metachromatic leukodystrophy
  • » Gaucher’s disease
  • » Nieman picks disease
  • » Osteopetrosis

Hemoglobinopathies

  • » Beta thalassemia major
  • » Sickle cell disease

Malignant diseases

  • » Acute lymphoblastic leukemia (ALL)
  • » Acute myelogenous leukemia (AML)
  • » Chronic myelogenous leukemia (CML)
  • » Juvenile myelomonocytic leukemia (JMML)
  • » Chronic Myelo- Monocytic Leukemia
  • » Chronic Lymphocytic Leukemia
  • » Myelodysplastic Syndrome
  • » Multiple Myeloma
  • » Hodgkins and Non Hodgkins Lymphoma
  • » Myeloproliferative disorders: Myelofibrosis

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